Version 5.4
Homo sapiens Gene: SLC27A6
Summary
InnateDB Gene IDBG-40136.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC27A6
Gene Name solute carrier family 27 (fatty acid transporter), member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000113396
Encoded Proteins
IDBP-40138
solute carrier family 27 (fatty acid transporter), member 6
IDBP-239900
solute carrier family 27 (fatty acid transporter), member 6
IDBP-478503
solute carrier family 27 (fatty acid transporter), member 6
IDBP-476395
solute carrier family 27 (fatty acid transporter), member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:128538013-129033642
Strand Forward strand
Band q23.3
Transcripts
ENST00000262462 ENSP00000262462
ENST00000395266 ENSP00000378684
ENST00000508645 ENSP00000421759
ENST00000506176 ENSP00000421024
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0031957 very long-chain fatty acid-CoA ligase activity
Biological Process
GO:0000038 very long-chain fatty acid metabolic process
GO:0001676 long-chain fatty acid metabolic process
GO:0008152 metabolic process
GO:0015909 long-chain fatty acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0042383 sarcolemma
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024600
View Gene Order
ENSBTAG00000004860
Not yet available
Pathways
NETPATH
REACTOME
REACT_23892
Transport of fatty acids pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa03320
PPAR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D6RAJ2
UniProt Splice Variant
Entrez Gene 28965
UniGene Hs.49765 Hs.599526 Hs.733430
RefSeq NM_001017372 NM_014031 XM_005271967 XM_005271968 XM_005271969 XM_005271970 XM_005271971
HUGO HGNC:11000
OMIM 604196
CCDS CCDS4145
HPRD 09173
IMGT
EMBL AC004038 AC004636 AC006959 AC008588 AC113387 AC114276
GenPept
RNA Seq Atlas 28965

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca