Version 5.4
Homo sapiens Gene: SLITRK1
Summary
InnateDB Gene IDBG-41480.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLITRK1
Gene Name SLIT and NTRK-like family, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178235
Encoded Proteins
IDBP-41482
SLIT and NTRK-like family, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This intronless gene encodes a member of the SLITRK protein family. These proteins are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. The protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:83877205-83882393
Strand Reverse strand
Band q31.1
Transcripts
ENST00000377084 ENSP00000366288
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007399 nervous system development
GO:0007409 axonogenesis
GO:0030534 adult behavior
GO:0035264 multicellular organism growth
GO:0042592 homeostatic process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000075478
View Gene Order
ENSBTAG00000038168
Not yet available
Cross-References
SwissProt Q96PX8
TrEMBL
UniProt Splice Variant
Entrez Gene 114798
UniGene Hs.415478 Hs.627477
RefSeq NM_001281503 NM_052910
HUGO HGNC:20297
OMIM 609678
CCDS CCDS9464
HPRD
IMGT
EMBL AB067497 AL355481 AY358289 BC051738
GenPept AAH51738 AAQ88656 BAB67803 CAC37488
RNA Seq Atlas 114798

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca