|Homo sapiens Gene: COTL1|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||coactosin-like 1 (Dictyostelium)|
coactosin-like 1 (Dictyostelium)
coactosin-like F-actin binding protein 1
|Useful resources||Stemformatics EHFPI ImmGen|
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 16:84565594-84618077|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|RNA Seq Atlas|