Version 5.4
Homo sapiens Gene: SLC43A1
Summary
InnateDB Gene IDBG-46661.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC43A1
Gene Name solute carrier family 43, member 1
Synonyms LAT3; PB39; POV1; R00504
Species Homo sapiens
Ensembl Gene ENSG00000149150
Encoded Proteins
IDBP-46663
solute carrier family 43, member 1
IDBP-596776
solute carrier family 43, member 1
IDBP-586410
solute carrier family 43, member 1
IDBP-585850
solute carrier family 43, member 1
IDBP-592782
solute carrier family 43, member 1
IDBP-592507
solute carrier family 43, member 1
IDBP-583901
solute carrier family 43, member 1
IDBP-599003
solute carrier family 43, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SLC43A1 belongs to the system L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:57484534-57515786
Strand Reverse strand
Band q12.1
Transcripts
ENST00000278426 ENSP00000278426
ENST00000528450 ENSP00000435673
ENST00000525764 ENSP00000435803
ENST00000529452
ENST00000533515
ENST00000530159 ENSP00000434312
ENST00000533066 ENSP00000435647
ENST00000524995 ENSP00000432361
ENST00000534105 ENSP00000432241
ENST00000533263 ENSP00000435486
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 2 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015175 neutral amino acid transmembrane transporter activity
GO:0015179 L-amino acid transmembrane transporter activity
Biological Process
GO:0006811 ion transport
GO:0006865 amino acid transport
GO:0015804 neutral amino acid transport
GO:0015807 L-amino acid transport
GO:0055085 transmembrane transport
GO:1902475 L-alpha-amino acid transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000027075
View Gene Order
Pathways
NETPATH
REACTOME
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O75387
TrEMBL A0A024R4Y3 B3KNL1 E9PJT8
UniProt Splice Variant
Entrez Gene 8501
UniGene Hs.591952 Hs.735724
RefSeq NM_001198810 NM_003627 XM_005274357 XM_005274358
HUGO HGNC:9225
OMIM 603733
CCDS CCDS7958
HPRD 07227
IMGT
EMBL AB103033 AF045584 AK027732 AP002893 BC001639 CH471076
GenPept AAC33004 AAH01639 BAD00152 BAG51373 EAW73750 EAW73751
RNA Seq Atlas 8501

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca