Homo sapiens Gene: AKR1E2
Summary
InnateDB Gene IDBG-47005.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKR1E2
Gene Name aldo-keto reductase family 1, member E2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165568
Encoded Proteins
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
aldo-keto reductase family 1, member E2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:4786629-4848062
Strand Forward strand
Band p15.1
Transcripts
ENST00000298375 ENSP00000298375
ENST00000334019 ENSP00000335034
ENST00000345253 ENSP00000335603
ENST00000441590
ENST00000462718
ENST00000474119 ENSP00000434437
ENST00000463345 ENSP00000436794
ENST00000487985 ENSP00000431625
ENST00000533295 ENSP00000435436
ENST00000525281
ENST00000525627
ENST00000532248 ENSP00000432947
ENST00000525572 ENSP00000433496
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0050571 1,5-anhydro-D-fructose reductase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q96JD6
TrEMBL E9PK93 G3V1C1
UniProt Splice Variant
Entrez Gene 83592
UniGene Hs.657944
RefSeq NM_001040177 NM_001271021 NM_001271025 XM_006717512 XM_006717513
HUGO HGNC:23437
OMIM
CCDS CCDS31134 CCDS59209 CCDS59210
HPRD
IMGT
EMBL AB040820 AB040821 AB040822 AB055603 AC018978 AC091817 AF263242 BC002862 CH471072
GenPept AAH02862 AAK58523 BAC54565 BAC54566 BAC54567 BAC54568 EAW86463
RNA Seq Atlas 83592