Version 5.4
Homo sapiens Gene: AKR1E2
Summary
InnateDB Gene IDBG-47005.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKR1E2
Gene Name aldo-keto reductase family 1, member E2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165568
Encoded Proteins
IDBP-47007
aldo-keto reductase family 1, member E2
IDBP-47009
aldo-keto reductase family 1, member E2
IDBP-47011
aldo-keto reductase family 1, member E2
IDBP-594979
aldo-keto reductase family 1, member E2
IDBP-602862
aldo-keto reductase family 1, member E2
IDBP-588793
aldo-keto reductase family 1, member E2
IDBP-589927
aldo-keto reductase family 1, member E2
IDBP-602024
aldo-keto reductase family 1, member E2
IDBP-587438
aldo-keto reductase family 1, member E2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:4786629-4848062
Strand Forward strand
Band p15.1
Transcripts
ENST00000298375 ENSP00000298375
ENST00000334019 ENSP00000335034
ENST00000345253 ENSP00000335603
ENST00000441590
ENST00000462718
ENST00000474119 ENSP00000434437
ENST00000463345 ENSP00000436794
ENST00000487985 ENSP00000431625
ENST00000533295 ENSP00000435436
ENST00000525281
ENST00000525627
ENST00000532248 ENSP00000432947
ENST00000525572 ENSP00000433496
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0050571 1,5-anhydro-D-fructose reductase activity
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045410
View Gene Order
ENSBTAG00000038260
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.657944
RefSeq NM_001040177 NM_001271021 NM_001271025 XM_006717512 XM_006717513
HUGO
OMIM
CCDS CCDS31134 CCDS59209 CCDS59210
HPRD 07472
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca