Version 5.4
Homo sapiens Gene: ZBTB20
Summary
InnateDB Gene IDBG-50911.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBTB20
Gene Name zinc finger and BTB domain containing 20
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181722
Encoded Proteins
IDBP-50913
zinc finger and BTB domain containing 20
IDBP-242914
zinc finger and BTB domain containing 20
IDBP-483641
zinc finger and BTB domain containing 20
IDBP-483493
zinc finger and BTB domain containing 20
IDBP-480216
zinc finger and BTB domain containing 20
IDBP-484158
zinc finger and BTB domain containing 20
IDBP-475619
zinc finger and BTB domain containing 20
IDBP-475476
zinc finger and BTB domain containing 20
IDBP-480926
zinc finger and BTB domain containing 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23776228
[Mus musculus] ZBTB20 inhibits transcription of IkBa to promote full TLR-triggered immunity. Zbtb20 null mice are resistant to endotoxin shock and sepsis.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:114338094-115147271
Strand Reverse strand
Band q13.31
Transcripts
ENST00000357258 ENSP00000349803
ENST00000393785 ENSP00000377375
ENST00000462705 ENSP00000420324
ENST00000481632 ENSP00000418092
ENST00000471418 ENSP00000419902
ENST00000474710 ENSP00000419153
ENST00000464560 ENSP00000417307
ENST00000479879
ENST00000470311 ENSP00000420684
ENST00000482689 ENSP00000419480
ENST00000463890
ENST00000486152
ENST00000480832
ENST00000491500
ENST00000492665
ENST00000470556
ENST00000463497
ENST00000488663
ENST00000468769
ENST00000470186
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022708
View Gene Order
ENSBTAG00000011928
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001164342 NM_001164343 NM_001164344 NM_001164345 NM_001164346 NM_001164347 NM_015642 XM_005247339 XM_005247340 XM_005247341 XM_006713577 XM_006713578
HUGO
OMIM
CCDS CCDS2981 CCDS54626
HPRD 05822
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca