Version 5.4
Bos taurus Gene: ZBTB20
Summary
InnateDB Gene IDBG-632638.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZBTB20
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011928
Encoded Proteins
IDBP-684275
zinc finger and BTB domain containing 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23776228
[Mus musculus] ZBTB20 inhibits transcription of IkBa to promote full TLR-triggered immunity. Zbtb20 null mice are resistant to endotoxin shock and sepsis.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181722:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:59420222-59721760
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015819 ENSBTAP00000015819
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000181722
View Gene Order
ENSMUSG00000022708
View Gene Order
Cross-References
SwissProt
TrEMBL F1MDT4
UniProt Splice Variant
Entrez Gene 508864
UniGene Bt.110475
RefSeq XM_002684783 XM_003581697 XM_003581698 XM_003581699 XM_003585639 XM_003585640 XM_003585641 XM_005196062 XM_005196063 XM_005196064 XM_005196065 XM_005196066 XM_005196067 XM_005196068 XM_005196069 XM_005196070 XM_005201363 XM_005201364 XM_005201365 XM_005201366 XM_005201367 XM_005201368 XM_005201369 XM_005201370 XM_005201371 XM_585702
HUGO HGNC:13503
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001406 DAAA02001407 DAAA02001408 DAAA02001409 DAAA02001410
GenPept
RNA Seq Atlas 508864

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca