InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: NDST1

Summary

InnateDB Gene

IDBG-53741.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDST1

Gene Name

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Synonyms

HSST; NST1

Species

Homo sapiens

Ensembl Gene

ENSG00000070614

Encoded Proteins

IDBP-53743

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

IDBP-475189

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

IDBP-482519

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

IDBP-483827

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

IDBP-474636

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:150485818-150558211

Strand

Forward strand

Band

q33.1

Transcripts

ENST00000261797	ENSP00000261797
ENST00000522491	ENSP00000429966
ENST00000519157	ENSP00000427813
ENST00000524161
ENST00000523767	ENSP00000428604
ENST00000518299	ENSP00000430258
ENST00000518346
ENST00000521752
ENST00000624156

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0008146	sulfotransferase activity
GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
GO:0016787	hydrolase activity
GO:0019213	deacetylase activity

Biological Process

GO:0000165	MAPK cascade
GO:0000271	polysaccharide biosynthetic process
GO:0005975	carbohydrate metabolic process
GO:0006024	glycosaminoglycan biosynthetic process
GO:0006954	inflammatory response
GO:0007224	smoothened signaling pathway
GO:0007585	respiratory gaseous exchange
GO:0008152	metabolic process
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0009887	organ morphogenesis
GO:0015012	heparan sulfate proteoglycan biosynthetic process
GO:0030203	glycosaminoglycan metabolic process
GO:0030210	heparin biosynthetic process
GO:0030900	forebrain development
GO:0030901	midbrain development
GO:0044281	small molecule metabolic process
GO:0048702	embryonic neurocranium morphogenesis
GO:0048703	embryonic viscerocranium morphogenesis