Version 5.4
Homo sapiens Gene: RBM22
Summary
InnateDB Gene IDBG-53894.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBM22
Gene Name RNA binding motif protein 22
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000086589
Encoded Proteins
IDBP-53896
RNA binding motif protein 22
IDBP-380254
RNA binding motif protein 22
IDBP-474461
RNA binding motif protein 22
IDBP-480415
RNA binding motif protein 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:150690794-150701107
Strand Reverse strand
Band q33.1
Transcripts
ENST00000199814 ENSP00000199814
ENST00000447771 ENSP00000412118
ENST00000520132
ENST00000522469
ENST00000518917 ENSP00000428154
ENST00000521248
ENST00000521594
ENST00000521464 ENSP00000430946
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005487 nucleocytoplasmic transporter activity
GO:0008270 zinc ion binding
GO:0017069 snRNA binding
GO:0036002 pre-mRNA binding
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
GO:0048306 calcium-dependent protein binding
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0000398 mRNA splicing, via spliceosome
GO:0033120 positive regulation of RNA splicing
GO:0035690 cellular response to drug
GO:0045292 mRNA cis splicing, via spliceosome
GO:0090316 positive regulation of intracellular protein transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024604
View Gene Order
ENSBTAG00000030366
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.713564
RefSeq NM_018047 XM_005268479
HUGO
OMIM
CCDS CCDS34278
HPRD 10186
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca