Version 5.4
Homo sapiens Gene: LSM14A
Summary
InnateDB Gene IDBG-547325.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LSM14A
Gene Name LSM14A, SCD6 homolog A (S. cerevisiae)
Synonyms C19orf13; FAM61A; RAP55; RAP55A
Species Homo sapiens
Ensembl Gene ENSG00000257103
Encoded Proteins
IDBP-377352
LSM14A, SCD6 homolog A (S. cerevisiae)
IDBP-601827
LSM14A, SCD6 homolog A (S. cerevisiae)
IDBP-586919
LSM14A, SCD6 homolog A (S. cerevisiae)
IDBP-766069
IDBP-807241
LSM14A, SCD6 homolog A (S. cerevisiae)
IDBP-761145
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:34172504-34229515
Strand Forward strand
Band q13.11
Transcripts
ENST00000433627 ENSP00000413964
ENST00000544216 ENSP00000446271
ENST00000540746 ENSP00000446451
ENST00000589878 ENSP00000468130
ENST00000590416
ENST00000588582
ENST00000585887 ENSP00000485334
ENST00000586157 ENSP00000466725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003690 double-stranded DNA binding
GO:0003725 double-stranded RNA binding
GO:0003727 single-stranded RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006417 regulation of translation
GO:0007275 multicellular organismal development
GO:0033962 cytoplasmic mRNA processing body assembly
GO:0039529 RIG-I signaling pathway
GO:0051607 defense response to virus
GO:0060340 positive regulation of type I interferon-mediated signaling pathway
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000066568
View Gene Order
ENSBTAG00000000630
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.407368 Hs.729627
RefSeq NM_001114093 NM_015578
HUGO
OMIM
CCDS CCDS12435 CCDS46040
HPRD 12697
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca