Version 5.4
Homo sapiens Gene: CCNG1
Summary
InnateDB Gene IDBG-56515.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCNG1
Gene Name cyclin G1
Synonyms CCNG
Species Homo sapiens
Ensembl Gene ENSG00000113328
Encoded Proteins
IDBP-56517
cyclin G1
IDBP-242629
cyclin G1
IDBP-482675
cyclin G1
IDBP-474975
cyclin G1
IDBP-481229
cyclin G1
IDBP-477750
cyclin G1
IDBP-475301
cyclin G1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:163437569-163446151
Strand Forward strand
Band q34
Transcripts
ENST00000340828 ENSP00000344635
ENST00000393929 ENSP00000377506
ENST00000512163 ENSP00000424315
ENST00000506186
ENST00000511683
ENST00000510097 ENSP00000423791
ENST00000511490 ENSP00000421132
ENST00000510664 ENSP00000422379
ENST00000512532
ENST00000504553 ENSP00000427086
ENST00000514367
ENST00000509143
ENST00000509425
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
Biological Process
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006949 syncytium formation
GO:0007067 mitotic nuclear division
GO:0007095 mitotic G2 DNA damage checkpoint
GO:0007420 brain development
GO:0010243 response to organonitrogen compound
GO:0016049 cell growth
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus
GO:0030425 dendrite
GO:0043025 neuronal cell body
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020326
View Gene Order
ENSBTAG00000006607
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
p53regulationpathway
p53 pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.587572 Hs.79101
RefSeq NM_004060 NM_199246
HUGO
OMIM
CCDS CCDS4360
HPRD 03345
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca