Version 5.4
Homo sapiens Gene: SNRPD2
Summary
InnateDB Gene IDBG-57903.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNRPD2
Gene Name small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
Synonyms Sm-D2; SMD2; SNRPD1
Species Homo sapiens
Ensembl Gene ENSG00000125743
Encoded Proteins
IDBP-57905
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
IDBP-246690
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
IDBP-766068
IDBP-763787
IDBP-762334
IDBP-765524
IDBP-763433
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:45687454-45692569
Strand Reverse strand
Band q13.32
Transcripts
ENST00000342669 ENSP00000342374
ENST00000391932 ENSP00000375798
ENST00000587367 ENSP00000465952
ENST00000590212 ENSP00000468247
ENST00000585392 ENSP00000465101
ENST00000588301 ENSP00000465216
ENST00000588599 ENSP00000466152
ENST00000587579
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 122 experimentally validated interaction(s) in this database.
Experimentally validated
Total 122 [view]
Protein-Protein 118 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0034660 ncRNA metabolic process
Cellular Component
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0005687 U4 snRNP
GO:0005689 U12-type spliceosomal complex
GO:0005829 cytosol
GO:0030532 small nuclear ribonucleoprotein complex
GO:0034709 methylosome
GO:0034715 pICln-Sm protein complex
GO:0034719 SMN-Sm protein complex
GO:0070062 extracellular vesicular exosome
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040824
View Gene Order
ENSBTAG00000012177
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_11066
snRNP Assembly pathway
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_1753
mRNA Splicing - Minor Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_11052
Metabolism of non-coding RNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL K7ERG4
UniProt Splice Variant
Entrez Gene 6633
UniGene Hs.713190 Hs.737619
RefSeq NM_004597 NM_177542 XM_005259180
HUGO HGNC:11159
OMIM 601061
CCDS CCDS33053 CCDS54281
HPRD 03038
IMGT
EMBL AC007191
GenPept
RNA Seq Atlas 6633

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca