Version 5.4
Homo sapiens Gene: CTNNA2
Summary
InnateDB Gene IDBG-58519.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTNNA2
Gene Name catenin (cadherin-associated protein), alpha 2
Synonyms CAP-R; CAPR; CT114; CTNR
Species Homo sapiens
Ensembl Gene ENSG00000066032
Encoded Proteins
IDBP-58523
catenin (cadherin-associated protein), alpha 2
IDBP-58525
catenin (cadherin-associated protein), alpha 2
IDBP-295437
catenin (cadherin-associated protein), alpha 2
IDBP-295435
catenin (cadherin-associated protein), alpha 2
IDBP-295432
catenin (cadherin-associated protein), alpha 2
IDBP-295428
catenin (cadherin-associated protein), alpha 2
IDBP-381175
catenin (cadherin-associated protein), alpha 2
IDBP-480392
catenin (cadherin-associated protein), alpha 2
IDBP-475916
catenin (cadherin-associated protein), alpha 2
IDBP-591856
catenin (cadherin-associated protein), alpha 2
IDBP-586697
catenin (cadherin-associated protein), alpha 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:79185231-80648861
Strand Forward strand
Band p12
Transcripts
ENST00000361291 ENSP00000355398
ENST00000343114 ENSP00000341500
ENST00000409971 ENSP00000387073
ENST00000402739 ENSP00000384638
ENST00000409266 ENSP00000387232
ENST00000409550 ENSP00000386587
ENST00000451966 ENSP00000400105
ENST00000466387 ENSP00000418191
ENST00000496251
ENST00000467488
ENST00000497804
ENST00000496558 ENSP00000419295
ENST00000493024
ENST00000465616
ENST00000467892
ENST00000541047 ENSP00000444675
ENST00000540488 ENSP00000441705
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0045296 cadherin binding
GO:0051015 actin filament binding
Biological Process
GO:0007155 cell adhesion
GO:0007409 axonogenesis
GO:0016337 single organismal cell-cell adhesion
GO:0021942 radial glia guided migration of Purkinje cell
GO:0042692 muscle cell differentiation
GO:0048813 dendrite morphogenesis
GO:0048854 brain morphogenesis
GO:0051149 positive regulation of muscle cell differentiation
GO:0051823 regulation of synapse structural plasticity
GO:0060134 prepulse inhibition
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005912 adherens junction
GO:0005913 cell-cell adherens junction
GO:0015629 actin cytoskeleton
GO:0016323 basolateral plasma membrane
GO:0030027 lamellipodium
GO:0030424 axon
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000063063
View Gene Order
Pathways
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
REACT_21402
CDO in myogenesis pathway
REACT_111045
Developmental Biology pathway
REACT_21303
Myogenesis pathway
KEGG
hsa04520
Adherens junction pathway
hsa05213
Endometrial cancer pathway
hsa04670
Leukocyte transendothelial migration pathway
hsa04530
Tight junction pathway
hsa05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
hsa05200
Pathways in cancer pathway
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL B9A010
UniProt Splice Variant
Entrez Gene 1496
UniGene Hs.167368
RefSeq NM_001164883 NM_001282597 NM_001282598 NM_001282599 NM_001282600 NM_004389 XM_006711949
HUGO HGNC:2510
OMIM 114025
CCDS CCDS42703 CCDS62944 CCDS62945 CCDS74531
HPRD 00228
IMGT
EMBL AC008067 AC010975 AC011741 AC011746 AC011754 AC016670 AC016716 AC018733 AC093322 AC096573 AC096753 AC104780 FJ695201
GenPept
RNA Seq Atlas 1496

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca