Version 5.4
Homo sapiens Gene: TGOLN2
Summary
InnateDB Gene IDBG-58918.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TGOLN2
Gene Name trans-golgi network protein 2
Synonyms TGN38; TGN46; TGN48; TGN51; TTGN2
Species Homo sapiens
Ensembl Gene ENSG00000152291
Encoded Proteins
IDBP-58920
trans-golgi network protein 2
IDBP-58922
trans-golgi network protein 2
IDBP-233532
trans-golgi network protein 2
IDBP-295408
trans-golgi network protein 2
IDBP-295409
trans-golgi network protein 2
IDBP-381393
trans-golgi network protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:85318020-85328425
Strand Reverse strand
Band p11.2
Transcripts
ENST00000282120 ENSP00000282120
ENST00000377386 ENSP00000366603
ENST00000398263 ENSP00000381312
ENST00000409232 ENSP00000386443
ENST00000409015 ENSP00000387035
ENST00000444342 ENSP00000391190
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030133 transport vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056429
View Gene Order
ENSBTAG00000038116
Not yet available
Pathways
NETPATH
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O43493
TrEMBL J3KQ45
UniProt Splice Variant
Entrez Gene 10618
UniGene Hs.629074 Hs.697237 Hs.698341 Hs.738852
RefSeq NM_001206840 NM_001206841 NM_001206844 NM_006464
HUGO HGNC:15450
OMIM 603062
CCDS CCDS46351 CCDS56126 CCDS56127
HPRD
IMGT
EMBL AC093162 AF027515 AF027516 AF029313 AF029314 AF029315 AF029316 AK126465 AK222829 AK223063 AK312479 BC008461 BC028219 BX640868 CH471053 U62390 X94333
GenPept AAB96906 AAB96907 AAB96908 AAC39539 AAC39541 AAC39542 AAH08461 AAH28219 AAY24095 BAC86559 BAD96549 BAD96783 BAG35383 CAA64002 CAE45926 EAW99535 EAW99536 EAW99539
RNA Seq Atlas 10618

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca