Homo sapiens Gene: TGOLN2
Summary
InnateDB Gene IDBG-58918.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TGOLN2
Gene Name trans-golgi network protein 2
Synonyms TGN38; TGN46; TGN48; TGN51; TTGN2;
Species Homo sapiens
Ensembl Gene ENSG00000152291
Encoded Proteins
trans-golgi network protein 2
trans-golgi network protein 2
trans-golgi network protein 2
trans-golgi network protein 2
trans-golgi network protein 2
trans-golgi network protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:85318020-85328425
Strand Reverse strand
Band p11.2
Transcripts
ENST00000282120 ENSP00000282120
ENST00000377386 ENSP00000366603
ENST00000398263 ENSP00000381312
ENST00000409232 ENSP00000386443
ENST00000409015 ENSP00000387035
ENST00000444342 ENSP00000391190
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030133 transport vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
trans-Golgi Network Vesicle Budding pathway
Clathrin derived vesicle budding pathway
Golgi Associated Vesicle Biogenesis pathway
Membrane Trafficking pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt O43493
TrEMBL
UniProt Splice Variant
Entrez Gene 10618
UniGene Hs.629074 Hs.697237 Hs.698341 Hs.738852
RefSeq NM_001206841 NM_001206840 NM_006464 NM_001206844
HUGO HGNC:15450
OMIM 603062
CCDS CCDS56126 CCDS46351 CCDS56127
HPRD 04343
IMGT
EMBL AC093162 AF027515 AF027516 AF029313 AF029314 AF029315 AF029316 AK126465 AK222829 AK223063 AK312479 BC008461 BC028219 BX640868 CH471053 U62390 X94333
GenPept AAB96906 AAB96907 AAB96908 AAC39539 AAC39541 AAC39542 AAH08461 AAH28219 AAY24095 BAC86559 BAD96549 BAD96783 BAG35383 CAA64002 CAE45926 EAW99535 EAW99536 EAW99539
RNA Seq Atlas 10618