Version 5.4
Homo sapiens Gene: ANO1
Summary
InnateDB Gene IDBG-62055.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ANO1
Gene Name anoctamin 1, calcium activated chloride channel
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131620
Encoded Proteins
IDBP-62057
anoctamin 1, calcium activated chloride channel
IDBP-62061
anoctamin 1, calcium activated chloride channel
IDBP-594592
anoctamin 1, calcium activated chloride channel
IDBP-592922
anoctamin 1, calcium activated chloride channel
IDBP-589874
anoctamin 1, calcium activated chloride channel
IDBP-603339
anoctamin 1, calcium activated chloride channel
IDBP-602115
anoctamin 1, calcium activated chloride channel
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:70078302-70189528
Strand Forward strand
Band q13.3
Transcripts
ENST00000355303 ENSP00000347454
ENST00000316296 ENSP00000319477
ENST00000531604 ENSP00000436392
ENST00000530676 ENSP00000435797
ENST00000530480 ENSP00000433445
ENST00000529913
ENST00000531349 ENSP00000432843
ENST00000531300 ENSP00000435868
ENST00000529636
ENST00000525494
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005227 calcium activated cation channel activity
GO:0005229 intracellular calcium activated chloride channel activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006812 cation transport
GO:0006821 chloride transport
GO:0007275 multicellular organismal development
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0055085 transmembrane transport
GO:0060438 trachea development
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0034707 chloride channel complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031075
View Gene Order
ENSBTAG00000009997
Not yet available
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_267716
Orphan transporters pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PNA7 E9PS90 Q9NW72
UniProt Splice Variant
Entrez Gene 55107
UniGene Hs.503074 Hs.608678
RefSeq XM_006718598 XM_006718599 XM_006718600 XM_006718601 XM_006718603 XM_006718605 NM_018043 XM_006718597
HUGO HGNC:21625
OMIM 610108
CCDS CCDS44663
HPRD 18202
IMGT
EMBL AK001123 AP000879
GenPept BAA91513
RNA Seq Atlas 55107

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca