Version 5.4
| Homo sapiens Gene: APPBP2 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-62307.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | APPBP2 | ||||||||||||||||||
| Gene Name | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | ||||||||||||||||||
| Synonyms | APP-BP2; HS.84084; PAT1 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000062725 | ||||||||||||||||||
| Encoded Proteins |
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer\'s disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 17:60443149-60526219 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q23.2 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME | |||||||||||||||||||
| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI |
Regulation of Androgen receptor activity
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| Cross-References | |||||||||||||||||||
| SwissProt | Q92624 | ||||||||||||||||||
| TrEMBL | A0A024QZ47 K7EIZ9 K7EN61 K7ENN3 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 10513 | ||||||||||||||||||
| UniGene | Hs.711594 Hs.84084 | ||||||||||||||||||
| RefSeq | NM_001282476 NM_006380 XM_006721639 | ||||||||||||||||||
| HUGO | HGNC:622 | ||||||||||||||||||
| OMIM | 605324 | ||||||||||||||||||
| CCDS | CCDS32699 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC011921 AC037475 AF017782 AK292227 BC018121 CH471179 D86981 | ||||||||||||||||||
| GenPept | AAC83973 AAH18121 BAA13217 BAF84916 EAW51406 EAW51407 | ||||||||||||||||||
| RNA Seq Atlas | 10513 | ||||||||||||||||||