Homo sapiens Gene: DEFB118 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-62650.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | DEFB118 | ||||||||
Gene Name | defensin, beta 118 | ||||||||
Synonyms | |||||||||
Species | Homo sapiens | ||||||||
Ensembl Gene | ENSG00000131068 | ||||||||
Encoded Proteins |
defensin, beta 118
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Dec 2010] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 20:31368618-31373923 | ||||||||
Strand | Forward strand | ||||||||
Band | q11.21 | ||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME |
Beta defensins pathway
Defensins pathway
Innate Immune System pathway
Immune System pathway
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KEGG | |||||||||
INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | Q96PH6 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 117285 | ||||||||
UniGene | Hs.274124 | ||||||||
RefSeq | NM_054112 | ||||||||
HUGO | HGNC:16196 | ||||||||
OMIM | 607650 | ||||||||
CCDS | CCDS13177 | ||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | AF347073 AF529415 AL031650 AY122471 BC117378 | ||||||||
GenPept | AAI17379 AAL27987 AAM93913 AAQ09524 CAI18885 | ||||||||
RNA Seq Atlas | 117285 | ||||||||