Version 5.4
| Homo sapiens Gene: DEFB118 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-62650.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | DEFB118 | ||||||||
| Gene Name | defensin, beta 118 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000131068 | ||||||||
| Encoded Proteins |
defensin, beta 118
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Dec 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 20:31368618-31373923 | ||||||||
| Strand | Forward strand | ||||||||
| Band | q11.21 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Beta defensins pathway
Defensins pathway
Innate Immune System pathway
Immune System pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q96PH6 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 117285 | ||||||||
| UniGene | Hs.274124 | ||||||||
| RefSeq | NM_054112 | ||||||||
| HUGO | HGNC:16196 | ||||||||
| OMIM | 607650 | ||||||||
| CCDS | CCDS13177 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF347073 AF529415 AL031650 AY122471 BC117378 | ||||||||
| GenPept | AAI17379 AAL27987 AAM93913 AAQ09524 CAI18885 | ||||||||
| RNA Seq Atlas | 117285 | ||||||||