InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLIT3

Summary

InnateDB Gene

IDBG-628374.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLIT3

Gene Name

slit homolog 3 protein precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000017746

Encoded Proteins

IDBP-679737

slit homolog 3 (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184347:
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 20:324518-507045

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000049620

ENSBTAP00000046486

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0048495	Roundabout binding

Biological Process

GO:0007411	axon guidance
GO:0008285	negative regulation of cell proliferation
GO:0009887	organ morphogenesis
GO:0010629	negative regulation of gene expression
GO:0030308	negative regulation of cell growth
GO:0032870	cellular response to hormone stimulus
GO:0035385	Roundabout signaling pathway
GO:0048846	axon extension involved in axon guidance
GO:0050919	negative chemotaxis
GO:0051414	response to cortisol
GO:0061364	apoptotic process involved in luteolysis
GO:0070100	negative regulation of chemokine-mediated signaling pathway