Bos taurus Gene: SLIT3
Summary
InnateDB Gene IDBG-628374.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLIT3
Gene Name slit homolog 3 protein precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017746
Encoded Proteins
slit homolog 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184347:
The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:324518-507045
Strand Reverse strand
Band
Transcripts
ENSBTAT00000049620 ENSBTAP00000046486
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0048495 Roundabout binding
Biological Process
GO:0007411 axon guidance
GO:0008285 negative regulation of cell proliferation
GO:0009887 organ morphogenesis
GO:0010629 negative regulation of gene expression
GO:0030308 negative regulation of cell growth
GO:0032870 cellular response to hormone stimulus
GO:0035385 Roundabout signaling pathway
GO:0048846 axon extension involved in axon guidance
GO:0050919 negative chemotaxis
GO:0051414 response to cortisol
GO:0061364 apoptotic process involved in luteolysis
GO:0070100 negative regulation of chemokine-mediated signaling pathway
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Netrin-1 signaling pathway
Developmental Biology pathway
Axon guidance pathway
Netrin-1 signaling pathway
Axon guidance pathway
Developmental Biology pathway
KEGG
Axon guidance pathway
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MMM6
UniProt Splice Variant
Entrez Gene 615883
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049822 DAAA02049823 DAAA02049824 DAAA02049825 DAAA02049826 DAAA02049827
GenPept
RNA Seq Atlas 615883