Version 5.4
Bos taurus Gene: BT.53943
Summary
InnateDB Gene IDBG-628541.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.53943
Gene Name ectoderm-neural cortex protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000026369
Encoded Proteins
IDBP-679905
ectoderm-neural cortex protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171617:
This gene encodes a member of the kelch-related family of actin-binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2, and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:6836625-6848939
Strand Forward strand
Band
Transcripts
ENSBTAT00000037458 ENSBTAP00000037291
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010499 proteasomal ubiquitin-independent protein catabolic process
GO:0016567 protein ubiquitination
GO:0017148 negative regulation of translation
Cellular Component
GO:0005737 cytoplasm
GO:0031463 Cul3-RING ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000171617
View Gene Order
ENSMUSG00000041773
View Gene Order
Cross-References
SwissProt
TrEMBL F1MK88
UniProt Splice Variant
Entrez Gene 617091
UniGene Bt.53943
RefSeq NM_001078067
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049962
GenPept
RNA Seq Atlas 617091

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca