InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: MYOG

Summary

InnateDB Gene

IDBG-628573.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYOG

Gene Name

Myogenin

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006030

Encoded Proteins

IDBP-679938

Myogenin

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122180:
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:596920-599757

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000007923

ENSBTAP00000007923

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987	core promoter proximal region sequence-specific DNA binding
GO:0001047	core promoter binding
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0031490	chromatin DNA binding
GO:0043565	sequence-specific DNA binding
GO:0046983	protein dimerization activity
GO:0070888	E-box binding

Biological Process

GO:0001503	ossification
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007049	cell cycle
GO:0007275	multicellular organismal development
GO:0007517	muscle organ development
GO:0007519	skeletal muscle tissue development
GO:0008285	negative regulation of cell proliferation
GO:0010831	positive regulation of myotube differentiation
GO:0014737	positive regulation of muscle atrophy
GO:0014842	regulation of satellite cell proliferation
GO:0014873	response to muscle activity involved in regulation of muscle adaptation
GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation
GO:0014891	striated muscle atrophy
GO:0014894	response to denervation involved in regulation of muscle adaptation
GO:0014902	myotube differentiation
GO:0030154	cell differentiation
GO:0045663	positive regulation of myoblast differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048741	skeletal muscle fiber development
GO:0048743	positive regulation of skeletal muscle fiber development
GO:0071158	positive regulation of cell cycle arrest
GO:0071285	cellular response to lithium ion
GO:0071363	cellular response to growth factor stimulus
GO:0071392	cellular response to estradiol stimulus
GO:1901739	regulation of myoblast fusion