InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ELK4

Summary

InnateDB Gene

IDBG-628824.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ELK4

Gene Name

ETS domain-containing protein Elk-4

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004953

Encoded Proteins

IDBP-680213

ETS domain-containing protein Elk-4

IDBP-680214

ETS domain-containing protein Elk-4

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158711:
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:3208946-3219936

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000063964	ENSBTAP00000056094
ENSBTAT00000006514	ENSBTAP00000006514

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0070932	histone H3 deacetylation