Version 5.4
Bos taurus Gene: SH3D19
Summary
InnateDB Gene IDBG-629156.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3D19
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016813
Encoded Proteins
IDBP-680585
SH3 domain containing 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109686:
This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:6636917-6684756
Strand Forward strand
Band
Transcripts
ENSBTAT00000022368 ENSBTAP00000022368
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0070064 proline-rich region binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0022604 regulation of cell morphogenesis
GO:0051044 positive regulation of membrane protein ectodomain proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000109686
View Gene Order
ENSMUSG00000028082
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
REACT_209837
Membrane Trafficking pathway
REACT_232671
Golgi Associated Vesicle Biogenesis pathway
REACT_243409
trans-Golgi Network Vesicle Budding pathway
REACT_234979
Clathrin derived vesicle budding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BNW5
UniProt Splice Variant
Entrez Gene 535511
UniGene Bt.81517
RefSeq XM_002694316 XM_005194938 XM_005194939 XM_005194940 XM_005194941 XM_005194942 XM_005194943 XM_005194944 XM_005217479 XM_005217480 XM_005217481 XM_005217482 XM_005217483 XM_005217484 XM_005217485 XM_615615
HUGO HGNC:30418
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02044206
GenPept
RNA Seq Atlas 535511

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca