Bos taurus Gene: AADAT | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-629270.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | AADAT | ||||||||||||
Gene Name | kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | ||||||||||||
Synonyms | AADAT | ||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000010326 | ||||||||||||
Encoded Proteins |
kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109576:
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 8:1792852-1816770 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Lysine catabolism pathway
Tryptophan catabolism pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
Metabolism pathway
Metabolism of amino acids and derivatives pathway
Tryptophan catabolism pathway
Lysine catabolism pathway
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KEGG |
Tryptophan metabolism pathway
Lysine biosynthesis pathway
Lysine degradation pathway
Lysine biosynthesis pathway
Lysine degradation pathway
Tryptophan metabolism pathway
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INOH |
Lysine degradation pathway
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PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Bt.11485 | ||||||||||||
RefSeq | NM_001015551 XM_002689448 XM_005209789 XM_598886 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||