Bos taurus Gene: BT.68703
Summary
InnateDB Gene IDBG-629585.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.68703
Gene Name vacuolar protein-sorting-associated protein 36
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000004307
Encoded Proteins
vacuolar protein-sorting-associated protein 36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136100:
VPS36, VPS22 (SNF8; MIM 610904), and VPS25 (MIM 610907) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. VPS36, VPS22, and VPS25 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:21633580-21665112
Strand Forward strand
Band
Transcripts
ENSBTAT00000005646 ENSBTAP00000005646
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0043130 ubiquitin binding
Biological Process
Cellular Component
GO:0005764 lysosome
GO:0005768 endosome
GO:0005770 late endosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
Membrane Trafficking pathway
Membrane Trafficking pathway
Endosomal Sorting Complex Required For Transport (ESCRT) pathway
KEGG
Endocytosis pathway
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MT69
UniProt Splice Variant
Entrez Gene 511223
UniGene Bt.17824 Bt.68703
RefSeq NM_001098939 XM_005213609
HUGO HGNC:20312
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02032965
GenPept
RNA Seq Atlas 511223