Bos taurus Gene: OXCT1
Summary
InnateDB Gene IDBG-629731.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OXCT1
Gene Name succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000033186
Encoded Proteins
succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083720:
This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:32683996-32848723
Strand Forward strand
Band
Transcripts
ENSBTAT00000047142 ENSBTAP00000044368
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008260 3-oxoacid CoA-transferase activity
GO:0008410 CoA-transferase activity
GO:0016740 transferase activity
Biological Process
GO:0008152 metabolic process
GO:0042182 ketone catabolic process
GO:0046950 cellular ketone body metabolic process
GO:0046952 ketone body catabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Utilization of Ketone Bodies pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Ketone body metabolism pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Ketone body metabolism pathway
Utilization of Ketone Bodies pathway
KEGG
Valine, leucine and isoleucine degradation pathway
Butanoate metabolism pathway
Synthesis and degradation of ketone bodies pathway
Valine, leucine and isoleucine degradation pathway
Synthesis and degradation of ketone bodies pathway
Butanoate metabolism pathway
INOH
Butanoate metabolism pathway
Valine Leucine Isoleucine degradation pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.63855
RefSeq NM_001076070
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas