Version 5.4
Bos taurus Gene: NAT1
Summary
InnateDB Gene IDBG-630161.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAT1
Gene Name Arylamine N-acetyltransferase 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016473
Encoded Proteins
IDBP-681596
Arylamine N-acetyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171428:
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:38862140-38868825
Strand Reverse strand
Band
Transcripts
ENSBTAT00000048506 ENSBTAP00000045530
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004060 arylamine N-acetyltransferase activity
GO:0016407 acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000171428
View Gene Order
ENSMUSG00000051147
View Gene Order
Pathways
NETPATH
REACTOME
REACT_222472
Acetylation pathway
REACT_218176
Biological oxidations pathway
REACT_219139
Metabolism pathway
REACT_213008
Phase II conjugation pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_6732
Acetylation pathway
REACT_6959
Phase II conjugation pathway
REACT_111217
Metabolism pathway
REACT_13433
Biological oxidations pathway
REACT_243247
Phase II conjugation pathway
REACT_188937
Metabolism pathway
REACT_237536
Acetylation pathway
REACT_232343
Biological oxidations pathway
KEGG
hsa00232
Caffeine metabolism pathway
hsa00983
Drug metabolism pathway
mmu00232
Caffeine metabolism pathway
mmu00983
Drug metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q1JPA6
TrEMBL
UniProt Splice Variant
Entrez Gene 512603
UniGene Bt.22638
RefSeq NM_001075572 XM_005226162 XM_005226163 XM_005226164
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123764 BT025447
GenPept AAI23765 ABF57403
RNA Seq Atlas 512603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca