|Bos taurus Gene: IL16|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||Pro-interleukin-16 Interleukin-16|
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172349:
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
|Genomic Location||Chromosome 21:27527684-27606711|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.
|Pathway Predictions based on Human Orthology Data|
JAK STAT pathway and regulation pathway
GPCR signaling pathway
|UniProt Splice Variant|
|EMBL||BT026153 DAAA02052339 DAAA02052340 DAAA02052341 DAAA02052342|
|RNA Seq Atlas||506314|