Bos taurus Gene: MAN1A1
Summary
InnateDB Gene IDBG-630645.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAN1A1
Gene Name mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
Synonyms MAN1A1
Species Bos taurus
Ensembl Gene ENSBTAG00000024381
Encoded Proteins
mannosidase, alpha, class 1A, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111885:
This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:32093591-32262873
Strand Forward strand
Band
Transcripts
ENSBTAT00000061143 ENSBTAP00000053539
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 pathway
N-glycan trimming and elongation in the cis-Golgi pathway
Transport to the Golgi and subsequent modification pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
Transport to the Golgi and subsequent modification pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Asparagine N-linked glycosylation pathway
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 pathway
N-glycan trimming and elongation in the cis-Golgi pathway
KEGG
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BNG2
UniProt Splice Variant
Entrez Gene 530027
UniGene Bt.46510
RefSeq NM_001205972 XM_005210733
HUGO HGNC:6821
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025720 DAAA02025721 DAAA02025722
GenPept
RNA Seq Atlas 530027