Homo sapiens Gene: MAN1A1 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-95959.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | MAN1A1 | ||||||||||||
Gene Name | mannosidase, alpha, class 1A, member 1 | ||||||||||||
Synonyms | HUMM3; HUMM9; MAN9 | ||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Gene | ENSG00000111885 | ||||||||||||
Encoded Proteins |
mannosidase, alpha, class 1A, member 1
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. [provided by RefSeq, Jul 2012] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 6:119177209-119349761 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | q22.31 | ||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 pathway
N-glycan trimming and elongation in the cis-Golgi pathway
Transport to the Golgi and subsequent modification pathway
Asparagine N-linked glycosylation pathway
Post-translational protein modification pathway
Metabolism of proteins pathway
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KEGG |
N-Glycan biosynthesis pathway
Protein processing in endoplasmic reticulum pathway
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INOH | |||||||||||||
PID NCI | |||||||||||||
Cross-References | |||||||||||||
SwissProt | P33908 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 4121 | ||||||||||||
UniGene | Hs.102788 Hs.611797 | ||||||||||||
RefSeq | NM_005907 XM_005266986 | ||||||||||||
HUGO | HGNC:6821 | ||||||||||||
OMIM | 604344 | ||||||||||||
CCDS | CCDS5122 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AL022722 AL078600 X74837 | ||||||||||||
GenPept | CAA52831 CAB75695 CAI20315 | ||||||||||||
RNA Seq Atlas | 4121 | ||||||||||||