Bos taurus Gene: EPHX1
Summary
InnateDB Gene IDBG-630999.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPHX1
Gene Name epoxide hydrolase 1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000140
Encoded Proteins
epoxide hydrolase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143819:
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:29585792-29624037
Strand Forward strand
Band
Transcripts
ENSBTAT00000000159 ENSBTAP00000000159
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0033961 cis-stilbene-oxide hydrolase activity
Biological Process
GO:0006725 cellular aromatic compound metabolic process
GO:0014070 response to organic cyclic compound
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Metabolism of xenobiotics by cytochrome P450 pathway
Bile secretion pathway
Metabolism of xenobiotics by cytochrome P450 pathway
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3ZCJ6
UniProt Splice Variant
Entrez Gene 535293
UniGene Bt.59229
RefSeq NM_001034629 XM_005216831 XM_005216832 XM_005216833
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102117 DAAA02042660 DAAA02042661 DAAA02042662
GenPept AAI02118
RNA Seq Atlas 535293