Version 5.4
Bos taurus Gene: FXYD2
Summary
InnateDB Gene IDBG-631113.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FXYD2
Gene Name sodium/potassium-transporting ATPase subunit gamma
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009828
Encoded Proteins
IDBP-682617
sodium/potassium-transporting ATPase subunit gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137731:
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes the sodium/potassium-transporting ATPase subunit gamma. Mutations in this gene have been associated with Renal Hypomagnesemia-2. Alternatively spliced transcript variants have been described. Read-through transcripts have been observed between this locus and the upstream FXYD domain-containing ion transport regulator 6 (FXYD6, GeneID 53826) locus.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:28909315-28916825
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012957 ENSBTAP00000012957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
Biological Process
GO:0006811 ion transport
GO:0034220 ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000137731
View Gene Order
ENSMUSG00000059412
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_250224
Ion transport by P-type ATPases pathway
KEGG
hsa04260
Cardiac muscle contraction pathway
hsa04960
Aldosterone-regulated sodium reabsorption pathway
hsa04964
Proximal tubule bicarbonate reclamation pathway
hsa04972
Pancreatic secretion pathway
hsa04970
Salivary secretion pathway
hsa04976
Bile secretion pathway
hsa04974
Protein digestion and absorption pathway
hsa04973
Carbohydrate digestion and absorption pathway
mmu04260
Cardiac muscle contraction pathway
mmu04960
Aldosterone-regulated sodium reabsorption pathway
mmu04974
Protein digestion and absorption pathway
mmu04973
Carbohydrate digestion and absorption pathway
mmu04970
Salivary secretion pathway
mmu04976
Bile secretion pathway
mmu04964
Proximal tubule bicarbonate reclamation pathway
mmu04972
Pancreatic secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QLN3
UniProt Splice Variant
Entrez Gene 281773
UniGene
RefSeq NM_174320
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC148026 DAAA02040394 GJ062397
GenPept AAI48027 DAA22361
RNA Seq Atlas 281773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca