Version 5.4
Bos taurus Gene: ABCC12
Summary
InnateDB Gene IDBG-631404.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCC12
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000044191
Encoded Proteins
IDBP-682986
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140798:
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:16551061-16610345
Strand Reverse strand
Band
Transcripts
ENSBTAT00000060942 ENSBTAP00000053282
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0008152 metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000140798
View Gene Order
ENSMUSG00000036872
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa02010
ABC transporters pathway
mmu02010
ABC transporters pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BM99
UniProt Splice Variant
Entrez Gene 528068
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046324 DAAA02046325 DAAA02046326 DAAA02046327
GenPept
RNA Seq Atlas 101908947 528068

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca