Bos taurus Gene: ZNF423
Summary
InnateDB Gene IDBG-631535.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF423
Gene Name zinc finger protein 423
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017397
Encoded Proteins
zinc finger protein 423
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Mus musculus] The transcription factor Zfp423 is necessary for adipocyte activation and impaired adipogenesis is observed in Zfp423(nur12) mice.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102935:
The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins. It functions as a DNA-binding transcription factor by using distinct zinc fingers in different signaling pathways. Thus, it is thought that this gene may have multiple roles in signal transduction during development. Mutations in this gene are associated with nephronophthisis-14 and Joubert syndrome-19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:18041277-18392207
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023130 ENSBTAP00000023130
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
BMP2 signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL A6QNQ0
UniProt Splice Variant
Entrez Gene 508025
UniGene Bt.57862 Bt.88222
RefSeq NM_001101893 XM_005218490
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC148946 DAAA02046367 DAAA02046368 DAAA02046369 DAAA02046370 DAAA02046371 DAAA02046372 DAAA02046373 DAAA02046374 DAAA02046375 DAAA02046376 DAAA02046377 DAAA02046378 DAAA02046379
GenPept AAI48947
RNA Seq Atlas 508025