Version 5.4
| Bos taurus Gene: BT.23666 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-631746.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | BT.23666 | ||||||||
| Gene Name | coagulation factor V precursor | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000017722 | ||||||||
| Encoded Proteins |
coagulation factor V precursor
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198734:
This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 16:37973199-38045988 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Common Pathway pathway
Platelet degranulation pathway
Response to elevated platelet cytosolic Ca2+ pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Platelet activation, signaling and aggregation pathway
Hemostasis pathway
Platelet degranulation pathway
Hemostasis pathway
Platelet activation, signaling and aggregation pathway
Formation of Fibrin Clot (Clotting Cascade) pathway
Response to elevated platelet cytosolic Ca2+ pathway
Common Pathway pathway
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| KEGG |
Complement and coagulation cascades pathway
Complement and coagulation cascades pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1N0I3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 280687 | ||||||||
| UniGene | |||||||||
| RefSeq | XM_005216875 XM_005216877 | ||||||||
| HUGO | HGNC:3542 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02042850 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 280687 | ||||||||