Version 5.4
Bos taurus Gene: MPP1
Summary
InnateDB Gene IDBG-632136.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPP1
Gene Name 55 kDa erythrocyte membrane protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013046
Encoded Proteins
IDBP-683732
55 kDa erythrocyte membrane protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130830:
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:39003631-39036435
Strand Forward strand
Band
Transcripts
ENSBTAT00000017340 ENSBTAP00000017340
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0090022 regulation of neutrophil chemotaxis
Cellular Component
GO:0005622 intracellular
GO:0016020 membrane
GO:0030863 cortical cytoskeleton
GO:0032420 stereocilium
GO:0042995 cell projection
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000130830
View Gene Order
ENSMUSG00000031402
View Gene Order
Cross-References
SwissProt Q17QN6
TrEMBL
UniProt Splice Variant
Entrez Gene 510998
UniGene Bt.12870
RefSeq NM_001075484
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC118256
GenPept AAI18257
RNA Seq Atlas 510998

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca