Version 5.4
Bos taurus Gene: BT.75472
Summary
InnateDB Gene IDBG-632211.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.75472
Gene Name POU domain, class 3, transcription factor 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000024773
Encoded Proteins
IDBP-683808
POU domain, class 3, transcription factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184486:
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:51596537-51601433
Strand Reverse strand
Band
Transcripts
ENSBTAT00000034488 ENSBTAP00000034379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001105 RNA polymerase II transcription coactivator activity
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0008284 positive regulation of cell proliferation
GO:0008544 epidermis development
GO:0014002 astrocyte development
GO:0014044 Schwann cell development
GO:0021799 cerebral cortex radially oriented cell migration
GO:0021869 forebrain ventricular zone progenitor cell division
GO:0021979 hypothalamus cell differentiation
GO:0021985 neurohypophysis development
GO:0022011 myelination in peripheral nervous system
GO:0030182 neuron differentiation
GO:0040018 positive regulation of multicellular organism growth
GO:0045595 regulation of cell differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0050770 regulation of axonogenesis
GO:0071310 cellular response to organic substance
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000184486
View Gene Order
ENSMUSG00000095139
View Gene Order
Cross-References
SwissProt
TrEMBL E1BNU7
UniProt Splice Variant
Entrez Gene 783320
UniGene Bt.75472
RefSeq NM_001080348
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02026229 DAAA02026230
GenPept
RNA Seq Atlas 783320

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca