Version 5.4
Bos taurus Gene: GDA
Summary
InnateDB Gene IDBG-632242.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GDA
Gene Name guanine deaminase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011545
Encoded Proteins
IDBP-683842
guanine deaminase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119125:
This gene encodes an enzyme responsible for the hydrolytic deamination of guanine. Studies in rat ortholog suggest this gene plays a role in microtubule assembly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:48658281-48782109
Strand Forward strand
Band
Transcripts
ENSBTAT00000015339 ENSBTAP00000015339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008892 guanine deaminase activity
GO:0016787 hydrolase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Biological Process
GO:0006147 guanine catabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000119125
View Gene Order
ENSMUSG00000058624
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_2086
Purine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_111217
Metabolism pathway
REACT_263730
Purine metabolism pathway
REACT_188937
Metabolism pathway
REACT_245662
Metabolism of nucleotides pathway
REACT_253802
Purine catabolism pathway
KEGG
hsa00230
Purine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1MLX9
UniProt Splice Variant
Entrez Gene 525937
UniGene Bt.63428
RefSeq NM_001192620
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02022872 DAAA02022873
GenPept
RNA Seq Atlas 525937

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca