Version 5.4
Bos taurus Gene: S100A13
Summary
InnateDB Gene IDBG-632825.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol S100A13
Gene Name Protein S100-A13
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021378
Encoded Proteins
IDBP-684480
Protein S100-A13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000189171:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:16818414-16824125
Strand Forward strand
Band
Transcripts
ENSBTAT00000028499 ENSBTAP00000028499
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005507 copper ion binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008144 drug binding
GO:0008270 zinc ion binding
GO:0008289 lipid binding
GO:0017134 fibroblast growth factor binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0050786 RAGE receptor binding
Biological Process
GO:0006810 transport
GO:0015031 protein transport
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043303 mast cell degranulation
GO:0050663 cytokine secretion
GO:0050703 interleukin-1 alpha secretion
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0042629 mast cell granule
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000189171
View Gene Order
ENSMUSG00000042312
View Gene Order
Cross-References
SwissProt P79342
TrEMBL
UniProt Splice Variant
Entrez Gene 404146
UniGene Bt.36848
RefSeq NM_205800 XM_005203623 XM_005203624
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB001567 BC103266
GenPept AAI03267 BAA19411
RNA Seq Atlas 404146

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca