Version 5.4
Bos taurus Gene: BT.27146
Summary
InnateDB Gene IDBG-634057.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.27146
Gene Name cleavage and polyadenylation specificity factor subunit 6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007323
Encoded Proteins
IDBP-685809
cleavage and polyadenylation specificity factor subunit 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111605:
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is one subunit of a cleavage factor required for 3\' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3\' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:44765461-44793485
Strand Reverse strand
Band
Transcripts
ENSBTAT00000050636 ENSBTAP00000047307
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
Predicted by orthology
Total 56 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006378 mRNA polyadenylation
GO:0006397 mRNA processing
GO:0051262 protein tetramerization
Cellular Component
GO:0005634 nucleus
GO:0005849 mRNA cleavage factor complex
GO:0016020 membrane
GO:0030529 ribonucleoprotein complex
GO:0042382 paraspeckles
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000111605
View Gene Order
ENSMUSG00000055531
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121141
Signaling by FGFR1 fusion mutants pathway
REACT_121398
Signaling by FGFR mutants pathway
REACT_120736
Signaling by FGFR in disease pathway
REACT_120999
Signaling by FGFR1 mutants pathway
REACT_116125
Disease pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F2Z4E9
UniProt Splice Variant
Entrez Gene 768231
UniGene Bt.27146
RefSeq NM_001078106 XM_005206467
HUGO HGNC:13871
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02013246
GenPept
RNA Seq Atlas 768231

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca