Bos taurus Gene: BDH1
Summary
InnateDB Gene IDBG-634166.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BDH1
Gene Name D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000448
Encoded Proteins
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161267:
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:72572941-72608810
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000573 ENSBTAP00000000573
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003858 3-hydroxybutyrate dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Synthesis of Ketone Bodies pathway
Utilization of Ketone Bodies pathway
Ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TCR pathway
REACTOME
Metabolism of lipids and lipoproteins pathway
Ketone body metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Utilization of Ketone Bodies pathway
Synthesis of Ketone Bodies pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of Ketone Bodies pathway
Ketone body metabolism pathway
Utilization of Ketone Bodies pathway
KEGG
Synthesis and degradation of ketone bodies pathway
Butanoate metabolism pathway
Synthesis and degradation of ketone bodies pathway
Butanoate metabolism pathway
INOH
Butanoate metabolism pathway
PID BIOCARTA
PID NCI
FOXA2 and FOXA3 transcription factor networks
Cross-References
SwissProt Q02337
TrEMBL
UniProt Splice Variant
Entrez Gene 534090
UniGene Bt.49607
RefSeq NM_001034600
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103051
GenPept AAI03052
RNA Seq Atlas 534090
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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