Version 5.4
Bos taurus Gene: SST
Summary
InnateDB Gene IDBG-634621.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SST
Gene Name somatostatin precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017312
Encoded Proteins
IDBP-686392
somatostatin precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157005:
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:80250205-80251648
Strand Forward strand
Band
Transcripts
ENSBTAT00000023020 ENSBTAP00000023020
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0030334 regulation of cell migration
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157005
View Gene Order
ENSMUSG00000004366
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_250376
G alpha (i) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
hsa04971
Gastric acid secretion pathway
mmu04971
Gastric acid secretion pathway
INOH
INOH website
GPCR signaling pathway
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1N145
UniProt Splice Variant
Entrez Gene 280932
UniGene
RefSeq NM_173960
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001833
GenPept
RNA Seq Atlas 280932

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca