Bos taurus Gene: SLC2A4 | |||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||||||||||||||
InnateDB Gene | IDBG-634743.3 | ||||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||||
Gene Symbol | SLC2A4 | ||||||||||||||||||||||||||||||
Gene Name | Solute carrier family 2, facilitated glucose transporter member 4 | ||||||||||||||||||||||||||||||
Synonyms | GLUT4 | ||||||||||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000009190 | ||||||||||||||||||||||||||||||
Encoded Proteins |
Solute carrier family 2, facilitated glucose transporter member 4
|
||||||||||||||||||||||||||||||
Protein Structure | |||||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181856:
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008] |
||||||||||||||||||||||||||||||
Gene Information | |||||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||||
Genomic Location | Chromosome 19:27616793-27621455 | ||||||||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||||||||
Band | |||||||||||||||||||||||||||||||
Transcripts |
|
||||||||||||||||||||||||||||||
Interactions | |||||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
|
||||||||||||||||||||||||||||||
Gene Ontology | |||||||||||||||||||||||||||||||
Molecular Function |
|
||||||||||||||||||||||||||||||
Biological Process |
|
||||||||||||||||||||||||||||||
Cellular Component |
|
||||||||||||||||||||||||||||||
Orthologs | |||||||||||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||||||||||||||||||||||||
Pathways | |||||||||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||||||||
REACTOME |
Metabolism of carbohydrates pathway
SLC-mediated transmembrane transport pathway
Hexose transport pathway
Myoclonic epilepsy of Lafora pathway
Translocation of GLUT4 to the plasma membrane pathway
Transmembrane transport of small molecules pathway
Transcriptional regulation of white adipocyte differentiation pathway
Facilitative Na+-independent glucose transporters pathway
Glucose transport pathway
Glycogen storage diseases pathway
Metabolism pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Disease pathway
Developmental Biology pathway
Membrane Trafficking pathway
|
||||||||||||||||||||||||||||||
KEGG | |||||||||||||||||||||||||||||||
INOH | |||||||||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||||||
NETPATH |
Leptin pathway
|
||||||||||||||||||||||||||||||
REACTOME |
Facilitative Na+-independent glucose transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Glucose transport pathway
Hexose transport pathway
Translocation of GLUT4 to the plasma membrane pathway
Transcriptional regulation of white adipocyte differentiation pathway
Transmembrane transport of small molecules pathway
Developmental Biology pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
Disease pathway
Glycogen storage diseases pathway
Membrane Trafficking pathway
Transcriptional regulation of white adipocyte differentiation pathway
Disease pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Membrane Trafficking pathway
Metabolism pathway
Glucose transport pathway
Transmembrane transport of small molecules pathway
Hexose transport pathway
Glycogen storage diseases pathway
Developmental Biology pathway
Facilitative Na+-independent glucose transporters pathway
Myoclonic epilepsy of Lafora pathway
Translocation of GLUT4 to the plasma membrane pathway
Metabolism of carbohydrates pathway
|
||||||||||||||||||||||||||||||
KEGG |
Insulin signaling pathway pathway
Type II diabetes mellitus pathway
Adipocytokine signaling pathway pathway
Type II diabetes mellitus pathway
Insulin signaling pathway pathway
Adipocytokine signaling pathway pathway
|
||||||||||||||||||||||||||||||
INOH |
Insulin receptor signaling pathway
Insulin receptor signaling pathway
|
||||||||||||||||||||||||||||||
PID NCI |
Class I PI3K signaling events mediated by Akt
Arf6 trafficking events
Insulin-mediated glucose transport
|
||||||||||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||||
UniGene | Bt.4391 | ||||||||||||||||||||||||||||||
RefSeq | NM_174604 | ||||||||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||||||||
CCDS | |||||||||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||||||||