Version 5.4
Bos taurus Gene: CAPG
Summary
InnateDB Gene IDBG-635176.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPG
Gene Name Macrophage-capping protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005432
Encoded Proteins
IDBP-687007
Macrophage-capping protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000042493:
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:49423731-49438680
Strand Forward strand
Band
Transcripts
ENSBTAT00000007150 ENSBTAP00000007150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0030031 cell projection assembly
GO:0051693 actin filament capping
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000042493
View Gene Order
ENSMUSG00000056737
View Gene Order
Cross-References
SwissProt Q865V6
TrEMBL
UniProt Splice Variant
Entrez Gene 353121
UniGene Bt.5499
RefSeq NM_178574 XM_005212743 XM_005212744
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY219899 BC102160
GenPept AAI02161 AAO38847
RNA Seq Atlas 353121

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca