Version 5.4
Bos taurus Gene: WDPCP
Summary
InnateDB Gene IDBG-635497.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDPCP
Gene Name WD repeat-containing and planar cell polarity effector protein fritz homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005151
Encoded Proteins
IDBP-687344
WD repeat containing planar cell polarity effector
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143951:
This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:61759950-61969748
Strand Reverse strand
Band
Transcripts
ENSBTAT00000006794 ENSBTAP00000006794
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001822 kidney development
GO:0002093 auditory receptor cell morphogenesis
GO:0007224 smoothened signaling pathway
GO:0007399 nervous system development
GO:0010762 regulation of fibroblast migration
GO:0042384 cilium assembly
GO:0042733 embryonic digit morphogenesis
GO:0043010 camera-type eye development
GO:0044782 cilium organization
GO:0045184 establishment of protein localization
GO:0048568 embryonic organ development
GO:0051893 regulation of focal adhesion assembly
GO:0055123 digestive system development
GO:0060021 palate development
GO:0060541 respiratory system development
GO:0072358 cardiovascular system development
GO:0090521 glomerular visceral epithelial cell migration
GO:1900027 regulation of ruffle assembly
GO:2000114 regulation of establishment of cell polarity
Cellular Component
GO:0097541 axonemal basal plate
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143951
View Gene Order
ENSMUSG00000020319
View Gene Order
Cross-References
SwissProt
TrEMBL E1B8R8
UniProt Splice Variant
Entrez Gene 527992
UniGene Bt.23781
RefSeq NM_001206786 XM_005212781 XM_005212782 XM_005212783
HUGO HGNC:28027
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031408 DAAA02031409 DAAA02031410 DAAA02031411 DAAA02031412
GenPept
RNA Seq Atlas 527992

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca