Version 5.4
Bos taurus Gene: BNIP3L
Summary
InnateDB Gene IDBG-635626.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BNIP3L
Gene Name BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021307
Encoded Proteins
IDBP-687469
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 26253785
[Mus musculus] Mitophagy-inducing proteins Bnip3 and Bnip3l play a regulatory role in the generation of robust natural killer cell memory.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104765:
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein counteracts the apoptotic inducer BNIP3 and may play a role in tumor suppression. [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:74924184-74947549
Strand Forward strand
Band
Transcripts
ENSBTAT00000033862 ENSBTAP00000033770
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005521 lamin binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006915 apoptotic process
GO:0035694 mitochondrial protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043069 negative regulation of programmed cell death
GO:0051607 defense response to virus
GO:0097345 mitochondrial outer membrane permeabilization
Cellular Component
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104765
View Gene Order
ENSMUSG00000022051
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt Q3T013
TrEMBL
UniProt Splice Variant
Entrez Gene 534615
UniGene Bt.109771 Bt.64079 Bt.66140 Bt.888
RefSeq NM_001034614
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102612 BT030544
GenPept AAI02613 ABQ12984
RNA Seq Atlas 534615

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca