InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: NDEL1

Summary

InnateDB Gene

IDBG-635870.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDEL1

Gene Name

nuclear distribution protein nudE-like 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011994

Encoded Proteins

IDBP-687794

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

IDBP-687802

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166579:
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Mar 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:28637771-28672316

Strand

Forward strand

Band

Transcripts

ENSBTAT00000065091	ENSBTAP00000055614
ENSBTAT00000044619	ENSBTAP00000042103

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.

Predicted by orthology
Total	44 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0043014	alpha-tubulin binding
GO:0048487	beta-tubulin binding

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0001764	neuron migration
GO:0001833	inner cell mass cell proliferation
GO:0007059	chromosome segregation
GO:0007100	mitotic centrosome separation
GO:0008090	retrograde axon cargo transport
GO:0010975	regulation of neuron projection development
GO:0016477	cell migration
GO:0021799	cerebral cortex radially oriented cell migration
GO:0021955	central nervous system neuron axonogenesis
GO:0032864	activation of Cdc42 GTPase activity
GO:0047496	vesicle transport along microtubule
GO:0051642	centrosome localization
GO:0060052	neurofilament cytoskeleton organization
GO:1990138	neuron projection extension

Cellular Component

GO:0000776	kinetochore
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005815	microtubule organizing center
GO:0005875	microtubule associated complex
GO:0030424	axon
GO:0031252	cell leading edge
GO:0043203	axon hillock
GO:0060053	neurofilament cytoskeleton