InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ndel1

Summary

InnateDB Gene

IDBG-189118.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndel1

Gene Name

nuclear distribution gene E-like homolog 1 (A. nidulans)

Synonyms

2600006O07Rik; MITAP1; mNudel; NUDEL

Species

Mus musculus

Ensembl Gene

ENSMUSG00000018736

Encoded Proteins

IDBP-189120

nuclear distribution gene E-like homolog 1 (A. nidulans)

IDBP-189122

nuclear distribution gene E-like homolog 1 (A. nidulans)

IDBP-264040

nuclear distribution gene E-like homolog 1 (A. nidulans)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166579:
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Mar 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:68821434-68871858

Strand

Reverse strand

Band

Transcripts

ENSMUST00000018880	ENSMUSP00000018880
ENSMUST00000101017	ENSMUSP00000098579
ENSMUST00000108672	ENSMUSP00000104312
ENSMUST00000143899
ENSMUST00000144300
ENSMUST00000127469

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.

Experimentally validated
Total	24 [view]
Protein-Protein	24 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	40 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0032403	protein complex binding
GO:0043014	alpha-tubulin binding
GO:0048487	beta-tubulin binding
GO:0070012	oligopeptidase activity

Biological Process

GO:0000226	microtubule cytoskeleton organization
GO:0001764	neuron migration
GO:0001833	inner cell mass cell proliferation
GO:0006508	proteolysis
GO:0007059	chromosome segregation
GO:0007100	mitotic centrosome separation
GO:0008090	retrograde axon cargo transport
GO:0010975	regulation of neuron projection development
GO:0016477	cell migration
GO:0021799	cerebral cortex radially oriented cell migration
GO:0021955	central nervous system neuron axonogenesis
GO:0031175	neuron projection development
GO:0032864	activation of Cdc42 GTPase activity
GO:0045773	positive regulation of axon extension
GO:0047496	vesicle transport along microtubule
GO:0048680	positive regulation of axon regeneration
GO:0051081	nuclear envelope disassembly
GO:0051642	centrosome localization
GO:0060052	neurofilament cytoskeleton organization
GO:1990138	neuron projection extension

Cellular Component

GO:0000776	kinetochore
GO:0000777	condensed chromosome kinetochore
GO:0005635	nuclear envelope
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005815	microtubule organizing center
GO:0005819	spindle
GO:0005871	kinesin complex
GO:0005874	microtubule
GO:0005875	microtubule associated complex
GO:0030424	axon
GO:0031252	cell leading edge
GO:0043203	axon hillock
GO:0044297	cell body
GO:0060053	neurofilament cytoskeleton