Bos taurus Gene: BRF1
Summary
InnateDB Gene IDBG-635930.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRF1
Gene Name Uncharacterized protein
Synonyms ZFP36L1
Species Bos taurus
Ensembl Gene ENSBTAG00000012753
Encoded Proteins
BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185024:
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:71187494-71234136
Strand Reverse strand
Band
Transcripts
ENSBTAT00000044278 ENSBTAP00000041784
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
GO:0043488 regulation of mRNA stability
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3X7R9
UniProt Splice Variant
Entrez Gene 618161
UniGene
RefSeq
HUGO HGNC:11551
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02053372 DAAA02053373 DAAA02053374 DAAA02053375 DAAA02053376
GenPept
RNA Seq Atlas 618161