Version 5.4
Bos taurus Gene: CLEC5A
Summary
InnateDB Gene IDBG-636542.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC5A
Gene Name C-type lectin domain family 5 member A
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020453
Encoded Proteins
IDBP-688473
C-type lectin domain family 5, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000258227:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation. Alternative splice variants have been described but their full-length sequence has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:106059820-106070381
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027255 ENSBTAP00000027255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001618 virus receptor activity
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0002076 osteoblast development
GO:0009615 response to virus
GO:0033033 negative regulation of myeloid cell apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0045087 innate immune response
GO:0050715 positive regulation of cytokine secretion
Cellular Component
GO:0009986 cell surface
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000029915
View Gene Order
ENSG00000258227
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_230745
Immune System pathway
REACT_188188
DAP12 interactions pathway
REACT_147694
DAP12 interactions pathway
REACT_6802
Innate Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BNL9
UniProt Splice Variant
Entrez Gene 615201
UniGene Bt.111603
RefSeq NM_001206203 XM_005205880
HUGO HGNC:2054
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02011753
GenPept
RNA Seq Atlas 615201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca