InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: KCND1

Summary

InnateDB Gene

IDBG-637014.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCND1

Gene Name

Potassium voltage-gated channel subfamily D member 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000009024

Encoded Proteins

IDBP-688992

Potassium voltage-gated channel subfamily D member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102057:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle. [provided by RefSeq, Jul 2008]
This gene encodes a multipass membrane protein that comprises the pore subunit of the voltage-gated A-type potassium channel, which functions in the repolarization of membrane action potentials. Activity of voltage-gated potassium channels is important in a number of physiological processes, among them the regulation of neurotransmitter release, heart rate, insulin secretion, and smooth muscle contraction. [provided by RefSeq, Aug 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:92147628-92153617

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000011882

ENSBTAP00000011882

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005251	delayed rectifier potassium channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0051260	protein homooligomerization
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030425	dendrite
GO:0042995	cell projection